DeepChek®-TB RpoB/InhA Drug Resistance Assay

Compatibility with Next Generation Sequencing platforms

Any

Intended use

RUO – ISO-9001 manufacturing

Types of samples

Decontaminated and concentrated sputum sediments

Format

24 samples/kit

Content

PCR reagents (enzymes, master mixes, primers, dNTPs...), protocols for Sanger & NGS sequencing, Sanger & NGS software analyses for 24 samples via a Cloud access

Sensitivity

Study ongoing

Specificity

High

Reproducibility

>99%

Workflow

From sample to result in ~30 hours for NGS (depending on the platform)

Covered positions

inhA: codons 1 – 130 rpoB: codons 92 – 522

Compatible extraction methods

Automatic (MagNA Pure Compact Nucleic Acid Isolation Kit I), Manual (Manual extractions using QIAamp® Viral DNA - Qiagen)...

Data analysis and interpretation software

BacterioChek-TB

Available analyses

Amino-acid mutations detection, nucleotide changes detection, drug resistance, NGS-run quality report, clinical genotyping report...

Drug resistance

Isoniazid and rifampicin based on different up-to-date guidelines

Included services

Unlimited updates & upgrades of the software, support, training...

Options

Local servers, historical data import, integration with LIS and HIS, integration with sequencers, automation of the IT workflow, customization...

DeepChek®-TB RpoB/InhA Genotyping Assay

K-18-RPOBINHA